Chicago, IL (My Sportsbook) - Derek Lowe will try to match the American League lead for wins with 22 this evening when he leads the Boston Red Sox against the Chicago White Sox at Comiskey Park.

Lowe has won three straight and four of his last five outings to get near to Oakland's Barry Zito for the American League lead in wins. Lowe, Zito and Pedro Martinez are in a tight race for the AL Cy Young award.

Last time on the hill, Lowe limited Baltimore to 10 hits and two runs over seven frames. The righty struck out two and didn't permit a walk in the winning effort. Lowe has given up no more than three earned runs in any of his last five starts.

Lowe was outstanding against the White Sox in his only outing, allowing just two hits over eight innings. For his career, Lowe is 1-1 with a 2.40 ERA versus Chicago.

The Dearborn, MI native has been solid on the road this season, tallying a 12-3 mark with a 2.81 ERA in 16 contests.

Chicago will counter with Rocky Biddle on the hill this evening. Biddle has split his last two starts, including a loss to Kansas City last week. The righthander allowed four hits and two runs over six innings, while fanning three and walking two.

Biddle will be facing the Red Sox for the first time this season. For his Biddle will be facing the Red Sox for the first time this season. For his career, Biddle is 0-1 with a 7.71 ERA.

Boston kept its very slim playoff hopes alive with a 4-2 win over Chicago on Tuesday. Anaheim lost to Texas on Tuesday, narrowing the difference to five for the wild card with five contests to play.

Casey Fossum pitched six strong innings and paced the Red Sox to the victory. Casey Fossum pitched six strong innings and paced the Red Sox to the victory. Fossum (5-4) surrendered just two runs on six hits, with two walks and three strikeouts. He improved to 3-1 in his last five starts. Ugueth Urbina pitched a perfect ninth, including two strikeouts, to earn his 39th save of the season.

Manny Ramirez and Jason Varitek each had RBI singles in a four-run sixth. Johnny Damon had two hits for the Red Sox, who won their fifth straight -- all on the road. Ramirez extended his hitting streak to 10 games. He finished 1- for-2 with two walks to improve his average to .345.

Frank Thomas and Joe Crede both homered for the White Sox, who had a three- game winning streak halted.

Jon Garland (12-12) had a personal two-game winning streak snapped, allowing four runs on four hits in 5 2/3 innings, while walking five and striking out two.

These squads have split four meetings this year and have split 10 since the start of last season.

The Red Sox are 51-28 on the road and 19-15 versus the Central, while Chicago is 45-34 at home and 16-14 against East.